PeptiDream Reports Discovery Collaboration Agreement With Janssen

(RTTNews) - PeptiDream Inc. said that it has entered into a multi-target discovery and optimization collaboration with US-based Janssen Pharmaceuticals Inc., one of the Janssen Pharmaceutical Companies of Johnson & Johnson (JNJ).

As per the agreement, facilitated by Johnson & Johnson Innovation, PeptiDream will use its proprietary Peptide Discovery Platform System (PDPS) technology to identify macrocyclic/constrained peptides against multiple metabolic and cardiovascular targets of interest selected by Janssen, and to optimize hit peptides into therapeutic peptides or small molecule products. Janssen also holds an exercisable option to peptide-drug conjugate (PDC) use and applications.

Janssen will have the right to develop and commercialize all compounds resulting from the collaboration.

As per the terms of the agreement, PeptiDream would receive an undisclosed upfront payment and research funding and is eligible to receive preclinical, clinical, and commercialization milestone payments potentially totaling up to $1.15 billion. In addition, PeptiDream is eligible to receive royalties on sales of any products that arise from the collaboration.

Over the past seven years, PeptiDream has established funded discovery collaborations with 16 of the leading pharmaceutical companies; Amgen, AstraZeneca, Bristol-Myers-Squibb, Lilly, GlaxoSmithKline, Novartis, Mitsubishi Tanabe, Daiichi Sankyo, Merck, Sanofi, Teijin, Kyorin, Ipsen, Genentech, Shionogi, and Asahi Kasei all of which are active and ongoing. In addition, PeptiDream has transferred its PDPS discovery platform for broad use to Bristol-Myers-Squibb, Novartis, Lilly, and Genentech.