22.12.2021 13:37:10

Alnylam Pharma Files Clinical Trial Authorization Application For ALN-APP In The UK

(RTTNews) - Alnylam Pharmaceuticals, Inc. (ALNY) has submitted a Clinical Trial Authorization application to The Medicines and Healthcare Products Regulatory Agency in the United Kingdom to begin a phase 1 study of ALN-APP, an investigational RNAi therapeutic targeting amyloid precursor protein for the treatment of Alzheimer's disease and cerebral amyloid angiopathy.

Alnylam Pharmaceuticals plans to begin the phase 1 study in patients with early-onset Alzheimer's disease in early 2022, upon obtaining MHRA approval, and expects to report initial human data at or around year-end 2022.

ALN-APP, the first-ever RNAi therapeutic targeting CNS diseases, is being advanced in partnership with Regeneron as part of Alnylam Pharma's 2019 agreement.

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Alnylam Pharmaceuticals Inc. 250,70 -0,44% Alnylam Pharmaceuticals Inc.
Regeneron Pharmaceuticals Inc. 642,40 0,09% Regeneron Pharmaceuticals Inc.