Kenneth Coleman Named Chairman of Accelrys

"Speaking on behalf of the entire Board of Accelrys and ourexecutive management team, we are very pleased that Ken has acceptedthe role as Chairman and we look forward to his continued guidance andcounsel. I personally look forward to continuing to work closely withhim," said Mr. Mark J. Emkjer, president & CEO of Accelrys.

"I am honored to have been appointed to the position of Chairmanof the Board," said Mr. Coleman. "Accelrys is a technological leaderwith great potential, and I look forward to continuing to work withMark and my other fellow Board members to further strengthen theCompany's competitive position in the marketplace."

Forward Looking Statements

Statements contained in this press release relating to theCompany's intentions, hopes, beliefs, expectations or predictions ofthe future, including statements relating to strengthening theCompany's competitive position in the marketplace, are forward-lookingstatements. The Company's actual results could differ materially fromthese forward-looking statements, for a number of factors, includingdemand for the Company's products. Additional information concerningfactors that could cause actual results to differ materially fromthose in the forward-looking statements is contained from time to timein the Company's SEC filings, including but not limited to theCompany's Annual Report on Form 10-K for the year ended March 31, 2005and the Company's Quarterly Reports on Form 10-Q for the quartersended June 30, 2005 and September 30, 2005. The Company disclaims anyintention or obligation to revise any forward-looking statements,whether as a result of new information, future events or otherwise.

About Accelrys

Accelrys, Inc. (NASDAQ:ACCL) is a leading provider of software forcomputation, simulation, and the management and mining of scientificdata used by biologists, chemists and materials scientists, includingnanotechnology researchers for product design as well as drugdiscovery and development. Accelrys technology and services aredesigned to meet the needs of today's leading research organizations.The company is headquartered in San Diego, California. Its materialsresearch and development team is based at its European Headquartersand Centre of Excellence in Cambridge, UK. For more information seehttp://www.accelrys.com/.