Cornerstone Pharmaceuticals to Present New Data on CPI-613 at the American Society of Hematology 2016 Annual Meeting

CRANBURY, N.J., Nov. 21, 2016 /PRNewswire/ --

WHAT: CPI-613 is Cornerstone Pharmaceuticals' lead drug candidate, a first-in-class anticancer compound designed to disrupt the altered energy production pathways in cancer cells by targeting mitochondrial metabolism. It selectively targets the mitochondrial tricarboxylic acid (TCA) cycle, a process essential to tumor cell proliferation and survival. The two datasets are from the first reported studies of CPI-613-based combination therapies in patients with AML and T-cell NHL. 

ASH Abstract Details:

• TCA Cycle Inhibition by CPI-613 Increases Sensitivity to Chemotherapy in Older and Poor Risk Acute Myeloid Leukemia (AML)
  • Date/Time:Monday, December 5, 20166:00-8:00 PM PT
  • Session: 616. Acute Myeloid Leukemia: Novel Therapy, Excluding Transplantation: Poster III
  • Location: San Diego Convention Center, Hall GH
  • Abstract #: 4062
  • Scheduled Presenter:Timothy S. Pardee, M.D. Ph.D., Section on Hematology and Oncology, Comprehensive Cancer Center of Wake Forest Baptist Medical Center, Winston-Salem, N         
• Phase I Dose-Escalation Study of CPI-613, in Combination with Bendamustine, in Relapsed or Refractory T-Cell Non-Hodgkin Lymphoma
  • Date/Time:Monday, December 5, 2016, 6:00-8:00 PM PT
  • Session: 624. Hodgkin Lymphoma and T/NK Cell Lymphoma—Clinical Studies: Poster III
  • Location:San Diego Convention Center, Hall GH
  • Abstract #: 4163
  • Scheduled Presenter:Zanetta S. Lamar, M.D., Department of Hematology / Oncology, Wake Forest Baptist Medical Center, Winston-Salem, NC

WHO: Drs. Pardee and Lamar (primary investigators) will be available for media interviews upon request

WHERE: American Society of Hematology Annual Meeting, San Diego Convention Center, San Diego, California

CONTACT: Kara Golub, 609-456-0822 or kgolub@jfkhealth.com, for more information.

About Cornerstone Pharmaceuticals, Inc.

Cornerstone Pharmaceuticals, Inc. is a privately held, clinical-stage, oncology-focused pharmaceutical company committed to the development and commercialization of therapies that exploit the metabolic differences between normal cells and cancer cells. The company's investors include IDT Corporation (NYSE: IDT). Cornerstone's primary objective is to develop highly selective and effective agents with minimal toxic effects on normal cells and tissues. Cornerstone's first-in-class clinical lead compound, CPI-613 is being evaluated in multiple Phase I, I/II, and II clinical studies. The U.S. Food and Drug Administration (FDA) has designated CPI-613 an orphan drug for the treatment of acute myeloid leukemia (AML), pancreatic cancer and myelodysplastic syndromes (MDS).www.cornerstonepharma.com.

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SOURCE Cornerstone Pharmaceuticals