TxCell Participation at Final COST AFACTT Meeting

Regulatory News:

TxCell SA (Paris:TXCL) (FR0010127662 – TXCL), a developer of cellular immunotherapies based on regulatory T cells (Tregs) for inflammation, autoimmunity and transplantation, today announces its participation at the Final Conference of the European COST Consortium ‘Action to Focus & Accelerate Cell-based Tolerogenic Therapies’ (A FACTT) to be held on October 9-11, 2017 in Barcelona, Spain.

Li Zhou, PhD, Vice President Cell Engineering at TxCell, will be co-chairing the session dedicated to regulatory T cells taking place on October 9, 2017 at 11.45am CEST. Li Zhou will make an introduction on TxCell’s CAR-Treg technology at the start of the session.

In addition, Ignacio Anegon, MD, INSERM scientist and co-director of team number 2 at the Center for Research in Transplantation and Immunology (CRTI, Nantes, France), will give an oral presentation entitled ‘CD8+ Treg new players in allograft tolerance’¹ on October 9, 2017, at 2.40pm CEST.

In December 2016, TxCell gained exclusive worldwide rights to two patent families covering the new type of CD8+ Tregs identified by the CRTI for all autoimmune diseases and transplantation-related disorders.

The full conference program is available on the conference website www.afactt.eu.

About TxCell – www.txcell.com

TxCell is a biotechnology company that develops platforms for innovative, personalized T cell immunotherapies for the treatment of severe inflammatory and autoimmune diseases with high unmet medical need. TxCell is targeting transplant rejection as well as a range of autoimmune diseases (both T-cell and B-cell-mediated) including multiple sclerosis, lupus nephritis and bullous pemphigoid.

TxCell’s cellular immunotherapies are based on regulatory T lymphocytes (Tregs). Tregs are a T cell population discovered in the nineties for which anti-inflammatory properties have been demonstrated. Contrary to conventional approaches based on non-specific polyclonal Tregs, TxCell is exclusively developing engineered antigen-specific Tregs, where the antigen specificity is brought by a Chimeric Antigen Receptor (CAR) (CAR-Treg cells).

Based in Sophia-Antipolis, France, TxCell is listed on Euronext Paris and currently has 46 employees.

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This press release contains certain forward-looking statements relating to the business of TxCell, which shall not be considered per se as historical facts, including TxCell’s ability to develop, market, commercialize and achieve market acceptance for specific products, estimates for future performance and estimates regarding anticipated operating losses, future revenues, capital requirements, needs for additional financing. In addition, even if the actual results or development of TxCell are consistent with the forward-looking statements contained in this press release, those results or developments of TxCell may not be indicative of their in the future.

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¹ Ménoret S, Guillonneau C, Anegon I (presenting author), CD8+ Treg new players in allograft tolerance, oral presentation, Final COST AFACTT meeting, October 9-11, 2017, Barcelona, Spain.

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