01.09.2019 14:29:53

Press Release: Novartis PARAGON-HF trial suggests -2-

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References

[1] Solomon S, McMurray J, et al. Angiotensin-Neprilysin in Heart

Failure with Preserved Ejection Fraction. N Engl J Med. 2019; doi:

10.1056/NEJMoa1908655

[2] Ponikowski P, Voors A, et al. 2016 ESC Guidelines for the diagnosis

and treatment of acute and chronic heart failure. Eur Heart J.

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[3] Treatment for Heart Failure: Endpoints for Drug Development

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(CDER) and Center for Biologics Evaluation and Research (CBER). June

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July 17, 2019.

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[5] Seferovic P, Ponikowski P, Anker S, et al. Clinical practice update

on heart failure 2019: pharmacotherapy, procedures, devices and patient

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Inhibition in Acute Decompensated Heart Failure. N Engl J Med. 2018.

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[7] Chandra A, Lewis E, Claggertt B, et al. The Effects of

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[8] EMA. Entresto (sacubitril/valsartan). Summary of product

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Accessed July 2019.

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America. Circulation. 2017;136:e137-161. doi:

10.1161/CIR.0000000000000509.

[10] Solomon S, Rizkala A, et al. Angiotensin Receptor Neprilysin

Inhibition in Heart Failure with Preserved Ejection Fraction: Rationale

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[11] Solomon S, Zile M, et al. The angiotensin receptor neprilysin

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[12] Ndumele C, Matsushita K, et al. NT-proBNP and Heart Failure Risk

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[13] What is Heart Failure? American Heart Association. Website.

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[14] Savarese G, Lund L. Global Public Health Burden of Heart Failure.

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[16] Ejection Fraction Heart Failure Measurement. American Heart

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[17] Dunlay S, Roger V, et al. Epidemiology of heart failure with

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[18] Oktay A, Rich J, et al. The Emerging Epidemic of Heart Failure

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[20] Owan T, Hodge D, et al. Trends in prevalence and outcome of heart

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[21] Yancy C, Jessup M, et al. 2017 ACC/AHA/HFSA Focused Update of the

2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of

the American College of Cardiology/American Heart Association Task Force

on Clinical Practice Guidelines and the Heart Failure Society of

America. Circulation. 2017;136:e137-161. doi:

10.1161/CIR.0000000000000509.

[22] Langenickel T, Dole W. Angiotensin receptor-neprilysin inhibition

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[23] ENTRESTO [prescribing information]. East Hanover, NJ: Novartis

Pharmaceuticals Corp; November 2018.

[24] Desai A, Claggett B, et al. Influence of Sacubitril/Valsartan

(LCZ696) on 30-Day Readmission After Heart Failure Hospitalization.

JACC. 2016;68(3):241-248. doi: 10.1016/j.jacc.2016.04.047.

# # #

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(END) Dow Jones Newswires

September 01, 2019 08:30 ET (12:30 GMT)

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