Mannatech Presents Scientific Posters at Scripps Center for Integrative Medicine’s 6th Annual Natural Supplements Conference

Mannatech, Incorporated (NASDAQ: MTEX), a leading developer and provider of proprietary dietary supplements, weight management products and skin care solutions, today announced that the company’s research and development scientists presented four scientific posters at the Scripps Center for Integrative Medicine’s 6th Annual Natural Supplements Conference: An Evidence-Based Update from January 23-25, 2009.

Scientists were invited to present the results of their recent research at the conference’s poster competition. Mannatech devoted three posters to its Ambrotose^® product technology, and the fourth presented the results of open-label human study on Mannatech’s new supplement designed to help with fat loss, OsoLean™ powder. Dr. Allyn Byars, associate professor of physical therapy at Angelo State University, San Angelo, Texas, also presented a poster about Mannatech’s pre-exercise supplement, EM•PACT^® sports drink mix.

"It was an honor to participate and present our research to our peers at the Scripps Natural Supplements Conference again this year,” said Robert A. Sinnott, MNS, PhD, chief science officer and senior vice president for Mannatech. "This conference brings together experts in the field of integrative medicine to present science-based information about dietary supplementation, and we are always excited to be a part of it.”

Mannatech was a sponsor of this year’s conference and hosted a dinner that allowed faculty presenting at the event the opportunity to meet and network. The company also presented posters at the past four Annual Natural Supplements Conferences. Additionally, Mannatech-funded research won first and second place awards for Basic Science in 2006.

Based in La Jolla, Calif., the Scripps Center for Integrative Medicine is devoted to developing personalized programs for the unique needs of their patients by "blending traditional medicine with evidence-based complementary therapies and advanced technology.” The center also sponsors numerous conferences devoted to providing continuing medical education to healthcare professionals, including the Annual Natural Supplements Conference.

Faculty this year included Dr. Mary Ruggie, professor of public policy at Harvard University’s Kennedy School of Government, who delivered the keynote presentation: Dietary Supplements, Integrative Medicine, and the New Direction in Health Care. Other notable speakers included Dr. Paul Coates, director of NIH’s Office of Dietary Supplements; Dr. Paula Gardiner, assistant professor at Boston Medical Center; and Tieraona Low Dog, director of the fellowship at the Arizona Center for Integrative Medicine.

About Mannatech

Mannatech, Incorporated, is a global wellness solutions provider of innovative, high-quality, proprietary dietary supplements, weight management products and skin care solutions sold through independent Associates and Members located in the United States and the international markets of Canada, Australia, the United Kingdom, Japan, New Zealand, the Republic of Korea, Taiwan, Denmark, Germany, South Africa, and Singapore. For more information please visit www.mannatech.com or www.allaboutmannatech.com.

Please Note: This release contains "forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended, Section 21E of the Securities Exchange Act of 1934, as amended, and the Private Securities Litigation Reform Act of 1995. These forward-looking statements generally can be identified by use of phrases or terminology such as "intend” or other similar words or the negative of such terminology. Similarly, descriptions of Mannatech’s objectives, strategies, plans, goals or targets contained herein are also considered forward-looking statements. Mannatech believes this release should be read in conjunction with all of its filings with the United States Securities and Exchange Commission and cautions its readers that these forward-looking statements are subject to certain events, risks, uncertainties, and other factors. Some of these factors include, among others, Mannatech’s inability to attract and retain associates and members, increases in competition, litigation, regulatory changes, and its planned growth into new international markets. Although Mannatech believes that the expectations, statements, and assumptions reflected in these forward-looking statements are reasonable, it cautions readers to always consider all of the risk factors and any other cautionary statements carefully in evaluating each forward-looking statement in this release, as well as those set forth in its latest Annual Report on Form 10-K and Quarterly Report on Form 10-Q, and other filings filed with the United States Securities and Exchange Commission, including its current reports on Form 8-K. All of the forward-looking statements contained herein speak only as of the date of this release.